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New Alkoxy Flavone Derivatives Targeting Caspases: Synthesis and Antitumor Activity Evaluation

The antitumor activity of natural flavonoids has been exhaustively reported. Previously it has been demonstrated that prenylation of flavonoids allows the discovery of new compounds with improved antitumor activity through the activation of caspase-7 activity. The synthesis of twenty-five flavonoids...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Moreira, Joana, Ribeiro, Diana, Silva, Patrícia M. A., Nazareth, Nair, Monteiro, Madalena, Palmeira, Andreia, Saraiva, Lucília, Pinto, Madalena, Bousbaa, Hassan, Cidade, Honorina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337158/
https://ncbi.nlm.nih.gov/pubmed/30602686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24010129
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