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Development of a Transcriptional Amplification System Based on the PEG3 Promoter to Target Androgen Receptor-Positive and -Negative Prostate Cancer Cells

Localized prostate cancer (PCa) is often curable, whereas metastatic disease treated by castration inevitably progresses toward castration-resistant PCa (CRPC). Most CRPC treatments target androgen receptor (AR) signaling. However, not all CRPC cells rely on AR activity for survival and proliferatio...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jain, Pallavi, Clermont, Pier-Luc, Desmeules, Francis, Zoubeidi, Amina, Neveu, Bertrand, Pouliot, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337121/
https://ncbi.nlm.nih.gov/pubmed/30626088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20010216
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