Extrasynaptic α(5)GABA(A) receptors on proprioceptive afferents produce a tonic depolarization that modulates sodium channel function in the rat spinal cord

Activation of GABA(A) receptors on sensory axons produces a primary afferent depolarization (PAD) that modulates sensory transmission in the spinal cord. While axoaxonic synaptic contacts of GABAergic interneurons onto afferent terminals have been extensively studied, less is known about the functio...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Lucas-Osma, Ana M., Li, Yaqing, Lin, Shihao, Black, Sophie, Singla, Rahul, Fouad, Karim, Fenrich, Keith K., Bennett, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337028/
https://ncbi.nlm.nih.gov/pubmed/30256739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00499.2018
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