A Comparative Study of the Pharmacokinetics of Clozapine N-Oxide and Clozapine N-Oxide Hydrochloride Salt in Rhesus Macaques

Translating chemogenetic techniques from nonhuman primates to potential clinical applications has been complicated in part due to in vivo conversion of the chemogenetic actuator, clozapine N-oxide (CNO), to its pharmacologically active parent compound, clozapine, a ligand with known side effects, in...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Pharmacol Exp Ther
Asıl Yazarlar: Allen, Daicia C., Carlson, Timothy L., Xiong, Yan, Jin, Jian, Grant, Kathleen A., Cuzon Carlson, Verginia C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2019
Konular:
Neuropharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337003/
https://ncbi.nlm.nih.gov/pubmed/30523062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.252031
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller