Intraluminal pressure triggers myogenic response via activation of calcium spark and calcium-activated chloride channel in rat renal afferent arteriole

Myogenic contraction of renal arterioles is an important regulatory mechanism for renal blood flow autoregulation. We have previously demonstrated that integrin-mediated mechanical force increases the occurrence of Ca(2+) sparks in freshly isolated renal vascular smooth muscle cells (VSMCs). To furt...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Yip, Kay-Pong, Balasubramanian, Lavanya, Kan, Chen, Wang, Lei, Liu, Ruisheng, Ribeiro-Silva, Luisa, Sham, James S. K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336985/
https://ncbi.nlm.nih.gov/pubmed/30089032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00239.2018
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