Paradoxical arteriole constriction compromises cytosolic and mitochondrial oxygen delivery in the isolated saline-perfused heart

The isolated saline-perfused heart is used extensively to study cardiac physiology. Previous isolated heart studies have demonstrated lower tissue oxygenation compared with in vivo hearts based on myoglobin oxygenation and the mitochondrial redox state. These data, consistent with small anoxic regio...

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Dades bibliogràfiques
Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Giles, Abigail V., Sun, Junhui, Femnou, Armel N., Kuzmiak-Glancy, Sarah, Taylor, Joni L., Covian, Raul, Murphy, Elizabeth, Balaban, Robert S.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336976/
https://ncbi.nlm.nih.gov/pubmed/30311498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00493.2018
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