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Mechanisms responsible for reduced erythropoiesis during androgen deprivation therapy in men with prostate cancer

Androgen deprivation therapy (ADT) is a mainstay of treatment for prostate cancer (PCa). As androgens stimulate erythropoiesis, ADT is associated with a reduction in hematocrit, which in turn contributes to fatigue and related morbidity. However, the mechanisms involved in ADT-induced reduction in e...

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Veröffentlicht in:Am J Physiol Endocrinol Metab
Hauptverfasser: Gagliano-Jucá, Thiago, Pencina, Karol M., Ganz, Tomas, Travison, Thomas G., Kantoff, Philip W., Nguyen, Paul L., Taplin, Mary-Ellen, Kibel, Adam S., Li, Zhuoying, Huang, Grace, Edwards, Robert R., Nemeth, Elizabeta, Basaria, Shehzad
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336960/
https://ncbi.nlm.nih.gov/pubmed/30325657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00272.2018
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