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Methylation of LINE-1 in cell-free DNA serves as a liquid biopsy biomarker for human breast cancers and dog mammary tumors

Breast cancer (BC) is one of the most common cancers in both women and female dogs. Methylation changes of LINE-1 have been reported in human cancers. The aim of this study was to determine the hypomethylation of canine LINE-1 in liquid biopsies for canine mammary tumors (CMT) and to assess its diag...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Kang-Hoon, Shin, Tae-Jin, Kim, Wan-Hee, Cho, Je-Yoel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336845/
https://ncbi.nlm.nih.gov/pubmed/30655558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36470-5
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