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Methylation of LINE-1 in cell-free DNA serves as a liquid biopsy biomarker for human breast cancers and dog mammary tumors

Breast cancer (BC) is one of the most common cancers in both women and female dogs. Methylation changes of LINE-1 have been reported in human cancers. The aim of this study was to determine the hypomethylation of canine LINE-1 in liquid biopsies for canine mammary tumors (CMT) and to assess its diag...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Lee, Kang-Hoon, Shin, Tae-Jin, Kim, Wan-Hee, Cho, Je-Yoel
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336845/
https://ncbi.nlm.nih.gov/pubmed/30655558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36470-5
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