Interferon lambda protects the female reproductive tract against Zika virus infection

Although Zika virus (ZIKV) can be transmitted sexually and cause congenital birth defects, immune control mechanisms in the female reproductive tract (FRT) are not well characterized. Here we show that treatment of primary human vaginal and cervical epithelial cells with interferon (IFN)-α/β or IFN-...

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Pubblicato in:Nat Commun
Autori principali: Caine, Elizabeth A., Scheaffer, Suzanne M., Arora, Nitin, Zaitsev, Konstantin, Artyomov, Maxim N., Coyne, Carolyn B., Moley, Kelle H., Diamond, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336786/
https://ncbi.nlm.nih.gov/pubmed/30655513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07993-2
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