Fetal-derived macrophages dominate in adult mammary glands

Macrophages serve multiple functions including immune regulation, morphogenesis, tissue homeostasis and healing reactions. The current paradigm holds that mammary gland macrophages first arise postnatally during the prepubertal period from the bone marrow-derived monocytes. Here we delineate the ori...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Jäppinen, Norma, Félix, Inês, Lokka, Emmi, Tyystjärvi, Sofia, Pynttäri, Anne, Lahtela, Tiina, Gerke, Heidi, Elima, Kati, Rantakari, Pia, Salmi, Marko
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336770/
https://ncbi.nlm.nih.gov/pubmed/30655530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08065-1
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