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Crystal structure of a natural light-gated anion channelrhodopsin
The anion channelrhodopsin GtACR1 from the alga Guillardia theta is a potent neuron-inhibiting optogenetics tool. Presented here, its X-ray structure at 2.9 Å reveals a tunnel traversing the protein from its extracellular surface to a large cytoplasmic cavity. The tunnel is lined primarily by small...
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| 發表在: | eLife |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications, Ltd
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6336409/ https://ncbi.nlm.nih.gov/pubmed/30614787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41741 |
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