The pro-tumor effect of CD200 expression is not mimicked by agonistic CD200R antibodies

Tumor-infiltrating immune cells can impact tumor growth and progression. The inhibitory CD200 receptor (CD200R) suppresses the activation of myeloid cells and lack of this pathway results in a reduction of tumor growth, conversely a tumorigenic effect of CD200R triggering was also described. Here we...

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Publicado en:PLoS One
Autores principales: Pilch, Zofia, Tonecka, Katarzyna, Skorzynski, Marcin, Sas, Zuzanna, Braniewska, Agata, Kryczka, Tomasz, Boon, Louis, Golab, Jakub, Meyaard, Linde, Rygiel, Tomasz P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336379/
https://ncbi.nlm.nih.gov/pubmed/30653571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210796
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