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An interaction-based model for neuropsychiatric features of copy-number variants

Variably expressive copy-number variants (CNVs) are characterized by extensive phenotypic heterogeneity of neuropsychiatric phenotypes. Approaches to identify single causative genes for these phenotypes within each CNV have not been successful. Here, we posit using multiple lines of evidence, includ...

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Vydáno v:PLoS Genet
Hlavní autoři: Jensen, Matthew, Girirajan, Santhosh
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336245/
https://ncbi.nlm.nih.gov/pubmed/30653500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007879
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