Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3β activities

BACKGROUND: Epithelial-mesenchymal transition (EMT) occurs in the tumor microenvironment and presents an important mechanism of tumor cell intravasation, stemness acquisition, and metastasis. During metastasis, tumor cells enter the circulation to gain access to distant tissues, but how this fluid m...

詳細記述

保存先:
書誌詳細
出版年:Breast Cancer Res
主要な著者: Choi, Hye Yeon, Yang, Gwang-Mo, Dayem, Ahmed Abdal, Saha, Subbroto Kumar, Kim, Kyeongseok, Yoo, Youngbum, Hong, Kwonho, Kim, Jin-Hoi, Yee, Cassian, Lee, Kyung-Mi, Cho, Ssang-Goo
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335853/
https://ncbi.nlm.nih.gov/pubmed/30651129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-1071-2
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