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Bisulfite-free, single base-resolution analysis of 5-hydroxymethylcytosine in genomic DNA by chemical-mediated mismatch

5-Hydroxymethylcytosine (5hmC) is known as one of the vital players in nuclear reprogramming and the process of active DNA demethylation. Although the development of whole-genome sequencing methods for modified cytosine bases has burgeoned, the easily operated gene-specific loci detection of 5hmC ha...

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Vydáno v:Chem Sci
Hlavní autoři: Wang, Yafen, Zhang, Xiong, Wu, Fan, Chen, Zonggui, Zhou, Xiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335847/
https://ncbi.nlm.nih.gov/pubmed/30746092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04272a
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