Hearing analysis in heterozygous and homozygous klotho gene deficient mice

OBJECTIVE: To understand the crucial role of the klotho gene in hearing development in mouse models. METHODS: PCR was used to identify CBA mice with different genotypes, i.e. WT, heterozygous (klotho +/−) or homozygous (klotho −/−). Mice phenotype and weight were recorded postnatal 25 days (P-25) an...

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Bibliographic Details
Published in:J Otol
Main Authors: Yuan, Na, Qiu, Shiwei, Wang, Qian, Zhuang, Wei, Li, Guoping, Sun, Tiantian, Yang, Shiming, Qiao, Yuehua, Shi, Xi
Format: Artigo
Language:Inglês
Published: Chinese PLA General Hospital 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335471/
https://ncbi.nlm.nih.gov/pubmed/30671089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joto.2018.04.001
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