Cisplatin-induced vestibular hair cell lesion-less damage at high doses

Cisplatin, a widely used anticancer drug, damages hair cells in cochlear organotypic cultures at low doses, but paradoxically causes little damage at high doses resulting in a U-shaped dose-response function. To determine if the cisplatin dose-response function for vestibular hair cells follows a si...

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Bibliografiska uppgifter
I publikationen:J Otol
Huvudupphovsmän: Ding, Dalian, Jiang, Haiyan, Zhang, Jianhui, Xu, Xianrong, Qi, Weidong, Shi, Haibo, Yin, Shankai, Salvi, Richard
Materialtyp: Artigo
Språk:Inglês
Publicerad: Chinese PLA General Hospital 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335437/
https://ncbi.nlm.nih.gov/pubmed/30671086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joto.2018.08.002
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