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Ethyl Pyruvate Stimulates Regulatory T Cells and Ameliorates Type 1 Diabetes Development in Mice
Type 1 diabetes (T1D) is an autoimmune disease in which a strong inflammatory response causes the death of insulin-producing pancreatic β-cells, while inefficient regulatory mechanisms allow that response to become chronic. Ethyl pyruvate (EP), a stable pyruvate derivate and certified inhibitor of a...
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Gepubliceerd in: | Front Immunol |
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Hoofdauteurs: | , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Frontiers Media S.A.
2019
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6335294/ https://ncbi.nlm.nih.gov/pubmed/30687329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03130 |
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