Biomarkers and Bone Imaging Dynamics Associated with Clinical Outcomes of Oral Cabozantinib Therapy in Metastatic Castrate Resistant Prostate Cancer

BACKGROUND: Cabozantinib is a multitargeted tyrosine kinase inhibitor that demonstrated remarkable responses on bone scan in metastatic prostate cancer. Randomized trials failed to demonstrate statistically significant overall survival. We studied the dynamics of biomarker changes with imaging and b...

詳細記述

保存先:
書誌詳細
出版年:Clin Cancer Res
主要な著者: Vaishampayan, Ulka N., Podgorski, Izabela, Heilbrun, Lance K., Lawhorn-Crews, Jawana M., Dobson, Kimberlee C., Boerner, Julie, Stark, Karri, Smith, Daryn W., Heath, Elisabeth I., Fontana, Joseph A., Shields, Anthony F.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335157/
https://ncbi.nlm.nih.gov/pubmed/30327304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1473
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