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Expanding the base editing scope in rice by using Cas9 variants

Base editing is a novel genome editing strategy that enables irreversible base conversion at target loci without the need for double stranded break induction or homology‐directed repair. Here, we developed new adenine and cytosine base editors with engineered SpCas9 and SaCas9 variants that substant...

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Publicat a:Plant Biotechnol J
Autors principals: Hua, Kai, Tao, Xiaoping, Zhu, Jian‐Kang
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335069/
https://ncbi.nlm.nih.gov/pubmed/30051586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12993
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