Neurologic adverse events in patients with relapsed/refractory acute lymphoblastic leukemia treated with blinatumomab: management and mitigating factors

Neurologic events (NEs) have been reported during treatment with blinatumomab, a bispecific T cell engager (BiTE®) construct. We evaluated the occurrence, severity, and management of NEs; the relationship between NEs and blinatumomab dose; and the potential clinical risk factors in an open-label, si...

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Publicado en:Ann Hematol
Autores principales: Stein, Anthony S., Schiller, Gary, Benjamin, Ramsis, Jia, Catherine, Zhang, Alicia, Zhu, Min, Zimmerman, Zachary, Topp, Max S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2018
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334725/
https://ncbi.nlm.nih.gov/pubmed/30238148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-018-3497-0
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