PDCD4 Knockdown Induces Senescence in Hepatoma Cells by Up-Regulating the p21 Expression

While the over-expression of tumor suppressor programmed cell death 4 (PDCD4) induces apoptosis, it was recently shown that PDCD4 knockdown also induced apoptosis. In this study, we examined the cell cycle regulators whose activation is affected by PDCD4 knockdown to investigate the contribution of...

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Podrobná bibliografie
Vydáno v:Front Oncol
Hlavní autoři: Guo, Jing, Ozaki, Iwata, Xia, Jinghe, Kuwashiro, Takuya, Kojima, Motoyasu, Takahashi, Hirokazu, Ashida, Kenji, Anzai, Keizo, Matsuhashi, Sachiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334536/
https://ncbi.nlm.nih.gov/pubmed/30687637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00661
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