PDCD4 Knockdown Induces Senescence in Hepatoma Cells by Up-Regulating the p21 Expression

While the over-expression of tumor suppressor programmed cell death 4 (PDCD4) induces apoptosis, it was recently shown that PDCD4 knockdown also induced apoptosis. In this study, we examined the cell cycle regulators whose activation is affected by PDCD4 knockdown to investigate the contribution of...

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Bibliografiska uppgifter
I publikationen:Front Oncol
Huvudupphovsmän: Guo, Jing, Ozaki, Iwata, Xia, Jinghe, Kuwashiro, Takuya, Kojima, Motoyasu, Takahashi, Hirokazu, Ashida, Kenji, Anzai, Keizo, Matsuhashi, Sachiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Oncology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334536/
https://ncbi.nlm.nih.gov/pubmed/30687637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00661
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