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Downregulation of miRNA-214 in cancer-associated fibroblasts contributes to migration and invasion of gastric cancer cells through targeting FGF9 and inducing EMT

BACKGROUND: Cancer-associated fibroblasts (CAFs), one of the principal constituents of the tumor microenvironment, have a pivotal role in tumor progression. Dysregulation of microRNAs (miRNAs) in CAFs contributes to the tumor-promoting ability of CAFs. However, the mechanism underlying the involveme...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Wang, Ruifen, Sun, Yeqi, Yu, Wenwei, Yan, Yu, Qiao, Meng, Jiang, Ruiqi, Guan, Wenbin, Wang, Lifeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334467/
https://ncbi.nlm.nih.gov/pubmed/30646925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0995-9
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