Genistein inhibits stemness of SKOV3 cells induced by macrophages co-cultured with ovarian cancer stem-like cells through IL-8/STAT3 axis

BACKGROUND: Recent studies showed that macrophages co-cultured with ovarian cancer stem-like cells (OCSLCs) induced SKOV3 cell stemness via IL-8/STAT3 signaling. Genistein (GEN) demonstrates chemopreventive activity in inflammation-associated cancers. The present study aimed to examine whether and i...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Ning, Yingxia, Feng, Weifeng, Cao, Xiaocheng, Ren, Kaiqun, Quan, Meifang, Chen, A., Xu, Chang, Qiu, Yebei, Cao, Jianguo, Li, Xiang, Luo, Xin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334437/
https://ncbi.nlm.nih.gov/pubmed/30646963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-1010-1
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