Gabapentin as add-on to morphine for severe neuropathic or mixed pain in children from age 3 months to 18 years - evaluation of the safety, pharmacokinetics, and efficacy of a new gabapentin liquid formulation: study protocol for a randomized controlled trial

BACKGROUND: Gabapentin has shown efficacy in the treatment of chronic neuropathic or mixed pain in adults. Although pediatric pain specialists have extensive experience with gabapentin for the treatment of neuropathic pain, its use is off-label. Its efficacy and safety in this context have never bee...

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Enregistré dans:
Détails bibliographiques
Publié dans:Trials
Auteurs principaux: de Leeuw, Thomas G., Mangiarini, Laura, Lundin, Rebecca, Kaguelidou, Florentia, van der Zanden, Tjitske, Pasqua, Oscar Della, Tibboel, Dick, Ceci, Adriana, de Wildt, Saskia N.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Study Protocol
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334401/
https://ncbi.nlm.nih.gov/pubmed/30646965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-018-3169-3
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