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The Alteration of Subtelomeric DNA Methylation in Aging-Related Diseases

The telomere is located at the end of the chromosome and consists of a non-coding, repetitive DNA sequence. As the cell divides, the length of telomere gradually decreases. A very short telomere can terminate mitosis, and thus telomere length becomes a hallmark of cellular aging. The 500 kb region o...

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Bibliografiska uppgifter
I publikationen:Front Genet
Huvudupphovsmän: Hu, Haochang, Li, Bin, Duan, Shiwei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333653/
https://ncbi.nlm.nih.gov/pubmed/30687384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00697
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