Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder

Bipolar disorder (BD) is a serious mood disorder associated with circadian rhythm abnormalities. Risk for BD is genetically encoded and overlaps with systems that maintain circadian rhythms. Lithium is an effective mood stabilizer treatment for BD, but only a minority of patients fully respond to mo...

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Publicat a:Neuropsychopharmacology
Autors principals: McCarthy, Michael J., Wei, Heather, Nievergelt, Caroline M., Stautland, Andrea, Maihofer, Adam X., Welsh, David K., Shilling, Paul, Alda, Martin, Alliey-Rodriguez, Ney, Anand, Amit, Andreasson, Ole A., Balaraman, Yokesh, Berrettini, Wade H., Bertram, Holli, Brennand, Kristen J., Calabrese, Joseph R., Calkin, Cynthia V., Claasen, Ana, Conroy, Clara, Coryell, William H., Craig, David W., D’Arcangelo, Nicole, Demodena, Anna, Djurovic, Srdjan, Feeder, Scott, Fisher, Carrie, Frazier, Nicole, Frye, Mark A., Gage, Fred H., Gao, Keming, Garnham, Julie, Gershon, Elliot S., Glazer, Kara, Goes, Fernando, Goto, Toyomi, Harrington, Gloria, Jakobsen, Petter, Kamali, Masoud, Karberg, Elizabeth, Kelly, Marisa, Leckband, Susan G., Lohoff, Falk, McInnis, Melvin G., Mondimore, Francis, Morken, Gunnar, Nurnberger, John I., Obral, Sarah, Oedegaard, Ketil J., Ortiz, Abigail, Ritchey, Megan, Ryan, Kelly, Schinagle, Martha, Schoeyen, Helle, Schwebel, Candice, Shaw, Martha, Shekhtman, Tatyana, Slaney, Claire, Stapp, Emma, Szelinger, Szabolcs, Tarwater, Bruce, Zandi, Peter P., Kelsoe, John R.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333516/
https://ncbi.nlm.nih.gov/pubmed/30487653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0273-8
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