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Development of a human APOE knock-in mouse model for study of cognitive function after cancer chemotherapy

Cancer-related cognitive impairment in breast cancer patients exposed to multi-agent chemotherapy regimens is associated with the Apolipoprotein E4 (APOE4) allele. However, it is difficult to determine the effects of specific agents on cognitive impairment in human studies. We describe the developme...

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Vydáno v:Neurotox Res
Hlavní autoři: Speidell, Andrew P., Demby, Tamar, Lee, Yichien, Rodriguez, Olga, Albanese, Christopher, Mandelblatt, Jeanne, Rebeck, G. William
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333492/
https://ncbi.nlm.nih.gov/pubmed/30284204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-018-9954-7
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