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Elevated CSF GAP-43 is Alzheimer’s disease specific and associated with tau and amyloid pathology

INTRODUCTION: The level of the presynaptic protein growth-associated protein 43 (GAP-43) in cerebrospinal fluid (CSF) has previously been shown to be increased in Alzheimer’s disease (AD) and thus may serve as an outcome measure in clinical trials and facilitate earlier disease detection. METHODS: W...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Sandelius, Åsa, Portelius, Erik, Källén, Åsa, Zetterberg, Henrik, Rot, Uros, Olsson, Bob, Toledo, Jon B., Shaw, Leslie M., Lee, Virginia M. Y., Irwin, David J., Grossman, Murray, Weintraub, Daniel, Chen-Plotkin, Alice, Wolk, David A., McCluskey, Leo, Elman, Lauren, Kostanjevecki, Vesna, Vandijck, Manu, McBride, Jennifer, Trojanowski, John Q., Blennow, Kaj
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333489/
https://ncbi.nlm.nih.gov/pubmed/30321501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.08.006
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