Programmed secretion arrest and receptor-triggered toxin export during antibacterial contact-dependent growth inhibition

Contact-dependent growth inhibition (CDI) entails receptor-mediated delivery of CdiA-derived toxins into Gram-negative target bacteria. Using electron cryotomography, we show that each CdiA effector protein forms a filament extending ~33 nm from the cell surface. Remarkably, the extracellular filame...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Ruhe, Zachary C., Subramanian, Poorna, Song, Kiho, Nguyen, Josephine Y., Stevens, Taylor A., Low, David A., Jensen, Grant J., Hayes, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333426/
https://ncbi.nlm.nih.gov/pubmed/30388452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.10.033
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