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Wnt Signaling Is Required for the Maintenance of Human Limbal Stem/Progenitor Cells In Vitro

PURPOSE: A chemical approach to examine the role of Wnt signaling in maintaining the stemness and/or proliferation of limbal stem/progenitor cells (LSCs). METHODS: LSCs were isolated from human donor eyes and cultured as single cells for 12 to 14 days with the following small molecules: IIIC3, an an...

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Publicado en:Invest Ophthalmol Vis Sci
Main Authors: González, Sheyla, Oh, Denise, Baclagon, Elfren R., Zheng, Jie J., Deng, Sophie X.
Formato: Artigo
Idioma:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333110/
https://ncbi.nlm.nih.gov/pubmed/30640975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-25740
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