UBE2C Induces Cisplatin Resistance via ZEB1/2-Dependent Upregulation of ABCG2 and ERCC1 in NSCLC Cells

OBJECTIVES: Cisplatin (DDP) is one of the most commonly used chemotherapeutic drugs for several cancers, including non-small-cell lung cancer (NSCLC). However, resistance to DDP eventually develops, limiting its further application. New therapy targets are urgently needed to reverse DDP resistance....

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Detalhes bibliográficos
Publicado no:J Oncol
Main Authors: Wu, Yan, Jin, Dan, Wang, Xiaohong, Du, Jing, Di, Weihua, An, Jiajia, Shao, Cuijie, Guo, Jiwei
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333017/
https://ncbi.nlm.nih.gov/pubmed/30693031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8607859
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