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Regulatory network analysis reveals the oncogenesis roles of feed-forward loops and therapeutic target in T-cell acute lymphoblastic leukemia

BACKGROUND: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy. Aberrant expressed genes contribute to the development and progression of T-ALL. However, the regulation underlying their aberrant expression remains elusive. Dysregulated expression of transcription f...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Xia, Mengxuan, Zhang, Qiong, Luo, Mei, Li, Pan, Wang, Yingxue, Lei, Qian, Guo, An-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332896/
https://ncbi.nlm.nih.gov/pubmed/30646895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0469-0
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