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Synthesis and Preliminary Biological Evaluation of 1,3,5-Triazine Amino Acid Derivatives to Study Their MAO Inhibitors

Three series of 4,6-dimethoxy-, 4,6-dipiperidino- and 4,6-dimorpholino-1,3,5-triazin-2-yl) amino acid derivatives were synthesized and characterized. A preliminary study for their monoamine oxidase inhibitory activity showed that compounds 7, 18, and 25 had MAO-A inhibition activity comparable to th...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Khattab, Sherine N., Khalil, Hosam H., Bekhit, Adnan A., El-Rahman, Mohamed Mokbel Abd, El-Faham, Ayman, Albericio, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332092/
https://ncbi.nlm.nih.gov/pubmed/26364629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200915976
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