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Synthesis and Regioselective Reaction of Some Unsymmetrical Heterocyclic Chalcone Derivatives and Spiro Heterocyclic Compounds as Antibacterial Agents

A number of novel heterocyclic chalcone derivatives can be synthesized by thermal and microwave tools. Treatment of 4-(4-Acetylamino- and/or 4-bromo-phenyl)-4-oxobut-2-enoic acids with hydrogen peroxide in alkaline medium were afforded oxirane derivatives 2. Reaction of the epoxide 2 with 2-amino-5-...

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Publicado en:Molecules
Main Authors: El-Hashash, Maher A., Rizk, Sameh A., Atta-Allah, Saad R.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332078/
https://ncbi.nlm.nih.gov/pubmed/26690393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules201219827
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