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The Curcumin Analogue 1,5-Bis(2-hydroxyphenyl)-1,4-pentadiene-3-one Induces Apoptosis and Downregulates E6 and E7 Oncogene Expression in HPV16 and HPV18-Infected Cervical Cancer Cells

In an effort to study curcumin analogues as an alternative to improve the therapeutic efficacy of curcumin, we screened the cytotoxic potential of four diarylpentanoids using the HeLa and CaSki cervical cancer cell lines. Determination of their EC(50) values indicated relatively higher potency of 1,...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Paulraj, Felicia, Abas, Faridah, Lajis, Nordin H., Othman, Iekhsan, Syed Hassan, Sharifah, Naidu, Rakesh
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331910/
https://ncbi.nlm.nih.gov/pubmed/26132907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200711830
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