New Diethyl Ammonium Salt of Thiobarbituric Acid Derivative: Synthesis, Molecular Structure Investigations and Docking Studies

The synthesis of the new diethyl ammonium salt of diethylammonium(E)-5-(1,5-bis(4-fluorophenyl)-3-oxopent-4-en-1-yl)-1,3-diethyl-4,6-dioxo-2-thioxohexaydropyrimidin-5-ide 3 via a regioselective Michael addition of N,N-diethylthiobarbituric acid 1 to dienone 2 is described. In 3, the carboanion of th...

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Gepubliceerd in:Molecules
Hoofdauteurs: Barakat, Assem, Al-Majid, Abdullah Mohammed, Soliman, Saied M., Lotfy, Gehad, Ghabbour, Hazem A., Fun, Hoong-Kun, Wadood, Abdul, Warad, Ismail, Sloop, Joseph C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331823/
https://ncbi.nlm.nih.gov/pubmed/26610441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules201119710
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