Akt‐mediated phosphorylation of MICU1 regulates mitochondrial Ca(2+) levels and tumor growth

Although mitochondria play a multifunctional role in cancer progression and Ca(2+) signaling is remodeled in a wide variety of tumors, the underlying mechanisms that link mitochondrial Ca(2+) homeostasis with malignant tumor formation and growth remain elusive. Here, we show that phosphorylation at...

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Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Marchi, Saverio, Corricelli, Mariangela, Branchini, Alessio, Vitto, Veronica Angela Maria, Missiroli, Sonia, Morciano, Giampaolo, Perrone, Mariasole, Ferrarese, Mattia, Giorgi, Carlotta, Pinotti, Mirko, Galluzzi, Lorenzo, Kroemer, Guido, Pinton, Paolo
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331721/
https://ncbi.nlm.nih.gov/pubmed/30504268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899435
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