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Identification of novel pathogenic ABCA4 variants in a Han Chinese family with Stargardt disease

Stargardt disease (STGD1, OMIM 248200) is a common hereditary juvenile or early adult onset macular degeneration. It ultimately leads to progressive central vision loss. Here, we sought to identify gene mutations associated with STGD1 in a three-generation Han Chinese pedigree by whole exome sequenc...

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Detalles Bibliográficos
Publicado en:Biosci Rep
Main Authors: Xiang, Qin, Cao, Yanna, Xu, Hongbo, Guo, Yi, Yang, Zhijian, Xu, Lu, Yuan, Lamei, Deng, Hao
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331664/
https://ncbi.nlm.nih.gov/pubmed/30563929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180872
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