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Genome-wide association analyses of invasive pneumococcal isolates identify a missense bacterial mutation associated with meningitis

Bacterial mutations predisposing pneumococcus to causing meningitis, a more severe form of invasive pneumococcal disease (IPD), are largely unknown. Knowledge of such mutations may improve our understanding of pathogenesis and inform preventive strategies. Here we report a pneumococcal pbp1b gene mu...

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Bibliografske podrobnosti
izdano v:	Nat Commun
Main Authors:	Li, Yuan, Metcalf, Benjamin J., Chochua, Sopio, Li, Zhongya, Walker, Hollis, Tran, Theresa, Hawkins, Paulina A., Gierke, Ryan, Pilishvili, Tamara, McGee, Lesley, Beall, Bernard W.
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group UK 2019
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6331587/ https://ncbi.nlm.nih.gov/pubmed/30643125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07997-y
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Genome-wide association analyses of invasive pneumococcal isolates identify a missense bacterial mutation associated with meningitis

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