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Mutations Defining Patient Cohorts With Elevated PD-L1 Expression in Gastric Cancer

The immunotherapy agent pembrolizumab has been approved for gastric cancer (GC) patients with recurrent or advanced disease who are PD-L1 positive. Mutations in the primary lesion may drive the expression of immune targets thereby priming the tumor to therapeutic sensitivity. In this study, we aimed...

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Publicado en:Front Pharmacol
Autores principales: Menyhárt, Otília, Pongor, Lőrinc Sándor, Győrffy, Balázs
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331584/
https://ncbi.nlm.nih.gov/pubmed/30670970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01522
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