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In vivo effects of single or combined topical neuroprotective and regenerative agents on degeneration of retinal ganglion cells in rat optic nerve crush model

To determine the effectiveness of a single or a combination of topical neurotrophic factors (NFs) in protecting retinal ganglion cells (RGCs) in the rat optic nerve crush (ONC) model, the left ONC was performed to induce the death of the RGCs in adult Sprague-Dawley rats. The NFs studied were taurou...

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Publicado en:Sci Rep
Autores principales: Kitamura, Yuta, Bikbova, Guzel, Baba, Takayuki, Yamamoto, Shuichi, Oshitari, Toshiyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331543/
https://ncbi.nlm.nih.gov/pubmed/30643179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36473-2
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