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Ion quantification in liposomal drug products using high performance liquid chromatography

A simple, straightforward analytical method based on liquid chromatography has been optimized to quantify total, internal, and external ions in drug-loaded liposomal products. The quantification of ammonium and sulfate ions in Doxil is detailed; although, the methodology has been extrapolated to qua...

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Detalhes bibliográficos
Publicado no:J Pharm Biomed Anal
Main Authors: Wu, Jiewei, Crist, Rachael M., McNeil, Scott E., Clogston, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331219/
https://ncbi.nlm.nih.gov/pubmed/30502551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2018.11.048
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