ATR activated by EB virus facilitates chemotherapy resistance to cisplatin or 5-fluorouracil in human nasopharyngeal carcinoma

PURPOSE: Epstein–Barr virus (EBV) infection is closely associated with nasopharyngeal carcinoma (NPC) and increases the chemotherapy resistance of tumor cells. Although the mechanism by which EBV manipulates ataxia telangiectasia mutation (ATM)-mediated DNA damage response in NPC has been extensivel...

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Vydáno v:Cancer Manag Res
Hlavní autoři: Zhang, Bo, Cui, Bomiao, Du, Jintao, Shen, Xin, Wang, Kun, Chen, Jiao, Xiao, Liying, Sun, Chongkui, Li, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331066/
https://ncbi.nlm.nih.gov/pubmed/30666155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S187099
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