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A Strategy for Discovery and Verification of Candidate Biomarkers in Cerebrospinal Fluid of Preclinical Alzheimer’s Disease

Alzheimer’s disease (AD), a progressive neurodegenerative disease, is characterized by the accumulation of senile plaques, neurofibrillary tangles, and loss of synapses and neurons in the brain. The pathophysiological process of AD begins with a long asymptomatic phase, which provides a potential op...

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Bibliografski detalji
Izdano u:Front Mol Neurosci
Glavni autori: Zhong, Xiaofang, Wang, Jingxin, Carlsson, Cynthia, Okonkwo, Ozioma, Zetterberg, Henrik, Li, Lingjun
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330998/
https://ncbi.nlm.nih.gov/pubmed/30666187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00483
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