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Apatinib inhibits tumor growth and angiogenesis in PNET models

Angiogenesis has a pivotal role in the growth and metastasis of pancreatic neuroendocrine tumors (PNETs). Apatinib inhibits angiogenesis as a highly selective KDR inhibitor and has been used to treat advanced gastric cancer and malignancies in clinical settings. However, the efficacy of apatinib in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Endocr Connect
Hauptverfasser: Wu, Shan, Zhou, Jianjun, Guo, Jing, Hua, Zhan, Li, Jianchen, Wang, Zai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Bioscientifica Ltd 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330719/
https://ncbi.nlm.nih.gov/pubmed/30557852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-18-0397
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