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The Inhibition of Phosphoinositide-3 Kinases Induce Resolution of Inflammation in a Gout Model

Phosphoinositide-3 kinases (PI3Ks) are central signaling enzymes that are involved in many aspects of immune cell function. PI3Kγ and PI3Kδ are the major isoforms expressed in leukocytes. The role of PI3K isoforms in the resolution of inflammation is still poorly understood. Here, we investigated th...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Galvão, Izabela, Queiroz-Junior, Celso Martins, de Oliveira, Vivian Louise Soares, Pinho, Vanessa, Hirsch, Emilio, Teixeira, Mauro Martins
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330337/
https://ncbi.nlm.nih.gov/pubmed/30666201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01505
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