Similar Tenofovir Hair Concentrations in Men and Women after Directly-Observed Dosing of TDF/FTC: Implications for PrEP Adherence Monitoring

OBJECTIVES: Women likely require higher adherence than men to pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) for similar efficacy. Pharmacologic metrics of adherence predict efficacy better than self-report, but expected drug levels (adherence benchmarks...

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Pubblicato in:AIDS
Autori principali: KOSS, Catherine A., LIU, Albert Y., CASTILLO-MANCILLA, Jose, BACCHETTI, Peter, MCHUGH, Cricket, KUNCZE, Karen, MORROW, Mary, LOUIE, Alexander, SEIFERT, Sharon, OKOCHI, Hideaki, MAWHINNEY, Samantha, GANDHI, Monica, ANDERSON, Peter L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330141/
https://ncbi.nlm.nih.gov/pubmed/30212404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001935
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