Generalizing Polygenic Risk Scores from Europeans to Hispanics/Latinos

Polygenic risk scores (PRSs) are typically constructed as weighted sums of risk allele counts of single nucleotide polymorphisms (SNPs) associated with a disease or trait. PRSs are typically constructed based on published results from Genome-Wide Association Studies (GWASs), the majority of which ha...

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Publicado en:Genet Epidemiol
Main Authors: Grinde, Kelsey E., Qi, Qibin, Thornton, Timothy A., Liu, Simin, Shadyab, Aladdin H., Chan, Kei Hang K., Reiner, Alexander P., Sofer, Tamar
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330129/
https://ncbi.nlm.nih.gov/pubmed/30368908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22166
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