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Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation
The density-regulated protein (DENR) and the malignant T cell-amplified sequence 1 (MCT-1/MCTS1) oncoprotein support noncanonical translation initiation, promote translation reinitiation on a specific set of mRNAs with short upstream reading frames, and regulate ribosome recycling. DENR and MCT-1 fo...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6329987/ https://ncbi.nlm.nih.gov/pubmed/30584092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809688116 |
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